A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect
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Descrição
Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
Evolving insights on histone methylome regulation in human acute
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
Disordered epigenetic regulation in MLL-related leukemia
Epigenetic deregulation in myeloid malignancies - ScienceDirect
Co-inhibition of HDAC and MLL-menin interaction targets MLL
Epigenetic deregulation in myeloid malignancies - ScienceDirect
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
Designed to kill: novel menin-MLL inhibitors target MLL-rearranged
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
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